Author + information
- Robert O. Brandenburg, MD, FACC*,
- Emilio R. Giuliani, MD, FACC,
- Walter R. Wilson, MD and
- Joseph E. Geraci, MD
- ↵*Address for reprints: Robert O. Brandenburg, MD, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905.
Diagnosis and management of infective endocarditis have significantly changed in the past 25 years. Improved bacteriologie techniques have allowed detection of cases of infective endocarditis caused by unusual organisms. Bactericidal therapy has become available for patients with gram-negative endocarditis and antimicrobial therapy has improved. Echocardiography has become an important diagnostic and management aid, and cardiac valve replacement has dramatically improved the outlook for many patients.
- American College of Cardiology Foundation