Author + information
- Leonard S. Gettes, MD, FACC*
- ↵*Address for reprints: Leonard S. Gettes, MD, Division of Cardiology, 353 Burnett-Womack Building 229H, University of North Carolina, Chapel Hill, North Carolina 27514.
As a result of single fiber electrophysiologic studies, the clinical approach to the electrical behavior of the heart has improved. Three areas are examined: 1) the electrocardiographic waveform, 2) normal and abnormal cardiac rhythms, and 3) the mechanism of action of antiarrhythmic drugs. In each area, the results of single fiber studies have provided a conceptual framework for diagnostic and therapeutic decisions. These studies have also enabled investigators to test hypotheses formulated from clinical observations. It may be only a slight exaggeration to attribute many of our recent advances in each of the three areas to the development and use of the microelectrode.
This research was supported by Grant HL-23624 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
- American College of Cardiology Foundation