Author + information
- Received July 20, 1982
- Revision received November 10, 1982
- Accepted November 12, 1982
- Published online April 1, 1983.
- Kenneth A. Brown, MD,
- Charles A. Boucher, MD, FACC,
- Robert D. Okada, MD, FACC,
- Timothy E. Guiney, MD,
- John B. Newell, BA,
- H. William Strauss, MD, FACC and
- Gerald M. Pohost, MD, FACC1,*
- ↵1Address for reprints: Gerald M. Pohost, MD, Cardiac Unit, Massachusetts General Hospital, Boston, Massachusetts 02114.
Accurate prognostic information is important in determining optimal management of patients presenting for evaluation of chest pain. In this study, the ability of exercise thallium-201 myocardial imaging to predict future cardiac events (cardiovascular death or nonfatal myocardial infarction) was correlated with clinical, coronary and left ventricular angiographic and exercise electrocardiographic data in 139 consecutive, nonsurgically managed patients followed-up over a 3 to 5 year period (mean follow-up, 3.7 ± 0.9), using a logistic regression analysis. Among patients without prior myocardial infarction (100 of 139), the number of myocardial segments with transient thallium-201 defects was the only statistically significant predictor of future cardiac events when all patient variables were evaluated. Among patients with myocardial infarction before evaluation (39 of 139), angiographic ejection fraction was the only significant predictor of future cardiac events when all variables were considered. This study suggests an approach to evaluate the risk of future cardiac events in patients with possible ischemic heart disease.
↵* Dr. Pohost is an Established Investigator of the American Heart Association, Dallas, Texas.
This study was supported in part by U.S. Public Health Service Grants ilL 21751 and HL 26215 and Cardiovascular Nuclear Medicine Training Grant 1-IL 07416 of the National Institutes of Health, Bethesda, Maryland.
- Received July 20, 1982.
- Revision received November 10, 1982.
- Accepted November 12, 1982.
- American College of Cardiology Foundation