Author + information
- Received October 12, 1982
- Revision received December 7, 1982
- Accepted December 10, 1982
- Published online May 1, 1983.
- Bruno V. Manno, MD,
- A-Hamid Hakki, MD, FACC*,
- Abdulmassih S. Iskandrian, MD, FACC and
- Tom Hare, BS
- ↵*Address for reprints: A—Hamid Hakki, MD, Likoff Cardiovascular Institute of Hahnemann University, 230 North Broad Street, Philadelphia, Pennsylvania 19102.
To determine the prevalence and evaluate the significance of an upright T wave in precordial lead V1, the 12 lead electrocardiograms of 218 patients undergoing diagnostic catheterization for the evaluation of chest pain were reviewed. Of this total, 184 patients had severe coronary artery disease (≥ 75% luminal narrowing) and 34 patients had minimal or no coronary artery disease.
An upright T wave in lead V1(≥ 0.15 mV) was present in 3 subjects (9%) without coronary artery disease; in 19 (20%) of 96 patients with one vessel disease; in 14 (27%) of 51 patients with two vessel disease and in 13 (35%) of 37 patients with three vessel disease. Among the patients with one vessel disease, an upright T wave was more frequent in patients with left circumflex artery disease than in patients with left anterior descending or right coronary artery disease (probability [p] < 0.001). Among patients with two vessel disease, an upright T wave was more frequent in patients with disease of the right coronary and left circumflex coronary arteries than in the remaining patients (p < 0.005).
It is concluded that an upright T wave in precordial lead V1is common in patients with isolated left circumflex artery disease but is rare in those with isolated left anterior descending artery disease. Similarly, in patients with multivessel disease, an upright T wave is common when the left circumflex artery is diseased. This finding, along with other noninvasive tests, may prove useful in patient evaluation.
- Received October 12, 1982.
- Revision received December 7, 1982.
- Accepted December 10, 1982.
- American College of Cardiology Foundation