Author + information
- Received September 21, 1982
- Revision received November 23, 1982
- Accepted November 30, 1982
- Published online May 1, 1983.
- Francis G. Dunn, MD, FACC*,
- Wille Oigman, MD,
- Kirsten Sungaard-Riise, BS,
- Franz H. Messerli, MD, FACC,
- Hector Ventura, MD,
- Efrain Reisin, MD and
- Edward D. Frohlich, MD, FACC
- ↵*Address for reprints: Francis G. Dunn, MD, Ochsner Clinic, 1514 Jefferson Highway, New Orleans, Louisiana 70121.
Epidemiologic data point to racial differences in cardiac adaptation to hypertension. In this study, echocardiography and measurement of systemic hemodynamics were performed in 30 black and 30 white patients with untreated essential hypertension. Each black patient was matched with a white patient for age, sex and mean arterial pressure. Wall thickness measurements were similar, but left ventricular mass index was significantly increased in blacks (probability [p] < 0.05). There was a nonsignificant increase in the number of black patients with posterior wall thickness greater than 1.1 cm. Only in black patients was posterior wall thickness related to systolic (r = 0.45; p = 0.008) and diastolic (r = 0.44; p = 0.0042) pressure and to total peripheral resistance (r = 0.32; p < 0.046). Thus, although ventricular wall thickness changes are similar in black and white patients, qualitative differences exist in the cardiac adaptive process to systemic hypertension.
This work was supported in part by a drant-in-Aid (HL 22506) from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland
- Received September 21, 1982.
- Revision received November 23, 1982.
- Accepted November 30, 1982.
- American College of Cardiology Foundation