Author + information
- Received November 3, 1982
- Revision received January 18, 1983
- Accepted January 21, 1983
- Published online June 1, 1983.
- Gerald L. Wolf, PhD, MD* and
- John W. Hirshfeld Jr, MD, FACC
- ↵*Address for reprints: Gerald L. Wolf, MD, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104.
Renografin-76 and Hypaque-76 are both recommended for coronary arteriography. Both have the same osmolality and iodine concentration, but differ in their calcium binding properties. After selective right or left coronary arteriography in patients, Renografin-76 caused significantly more prolongation of the QTc interval than did Hypaque-76. Less calcium binding in the Hypaque formulation is probably responsible for its lesser effect on the QTc interval. This study suggests, but does not prove, that Hypaque-76 is safer than Renografin-76 for coronary arteriography.
- Received November 3, 1982.
- Revision received January 18, 1983.
- Accepted January 21, 1983.
- American College of Cardiology Foundation