Author + information
- Received October 19, 1982
- Revision received January 27, 1983
- Accepted February 9, 1983
- Published online June 1, 1983.
- Abdulmassih S. Iskandrian, MD, FACC*,
- A-Hamid Hakki, MD, FACC,
- Nicholas L. DePace, MD,
- Bruno Manno, MD and
- Bernard L. Segal, MD, FACC
- ↵*Address for reprints: Abdulmassih S. Iskandrian, MD, Likoff Cardio-vascular Institute, Hahnemann University and Hospital, 230 North Broad Street, Philadelphia, Pennsylvania 19102.
Radionuclide angiography permits evaluation of left ventricular performance during exercise. There are sever al factors that may affect the results in normal subjects and in patients with chronic coronary heart disease. Important among these are the selection criteria: age, sex, level of exercise, exercise end points, ejection fraction at rest and effects of pharmacologic agents. An abnormal ejection fraction response to exercise is not a specific marker for coronary heart disease but may be encountered in other cardiac diseases.
In addition to the diagnostic considerations, important prognostic data can be obtained. Further studies are needed to determine the prognostic implications of anatomic findings versus the functional abnormalities induced by exercise in patients with coronary artery disease.
- Received October 19, 1982.
- Revision received January 27, 1983.
- Accepted February 9, 1983.
- American College of Cardiology Foundation