Author + information
- Received August 10, 1987
- Revision received October 20, 1987
- Accepted November 4, 1987
- Published online April 1, 1988.
- Tohru Masuyama, MD∗∗,
- Kazuhisa Kodama, MD∗,
- Satoshi Nakatani, MD∗,
- Shinsuke Nanto, MD∗,
- Akira Kitabatake, MD† and
- Takenobu Kamada, MD†
- ↵∗Address for reprints: Tohru Masuyama, MD, Cardiology Division, Falk Cardiovascular Research Center, Stanford University School of Medicine, 300 Pasicur Drive, Stanford, California, 94305.
To determine the effects of changes in coronary stenosis on left ventricular diastolic filling, diastolic filling was serially examined before and after percutaneous transluminal coronary angioplasty using pulsed Doppler echocardiopraphy in 50 palients with stable exertional angina pecleris. Peak rapid fifting, velocity and the ratio of peak atrial tilling to peak rapid filling velocities were measured from the transmitral flow velocity pattern berore and 2 and 9 days after coronary angioplasty. Peak rapid filling velocity increased and the ratio of peak etrial filling to peak rapid filling velocities decreased gradually after coronary angioplasty. The improvement in left ventricular diastolic filling was greatr in patients with severe (>90%) coronary stenosis than in patients with mild (≤90%) coronary stenosis. In the long-term follow-up period, the improved left ventricular diastolic filling worsened in only 11 patients with marked progression to >99% coronary stenosis.
Thus, left ventricular diastolic filling Improved gradualy after coronary angloplasty, possibly reflecting postiwhemic “stunned” myocardium. Serial examinations of left ventricular diastolic filling with pulsed Doppler echocardiography may be a means of nonlnvasively assessing the temporal changes in the coronary stenosis and predicting the occurrence of coronary restenosis after coronary angioplasty.
☆ This study was presented in part at the 59th Annual Scientific Sessions of the American Heart Association, Dallas, Texas, November 1986.
- Received August 10, 1987.
- Revision received October 20, 1987.
- Accepted November 4, 1987.