Author + information
- Received October 19, 1987
- Revision received February 16, 1988
- Accepted March 9, 1988
- Published online August 1, 1988.
- Kevin J. Beatt, MRCP1,
- Hans E. Luijten, MD2,
- Pim J. de Feyter, MD,
- Marcel van den Brand, MD,
- Johan H.C. Reiber, PhD and
- Patrick W. Serruys, MD, FACC∗
- ↵∗Address for reprints: Patrick W. Serruys, MD, Thoraxcenter. Erasmus University and University Hospital Dijkzigt, Catheterization Laboratory and Laboratory for Clinical and Experimental Image Processing, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.
To determine the changes in stenotic and nonstenotic segments or a dilated coronary artery, detailed quantitative angiographic measurements were performed in 342 patients (398 lesions) immediately after angioplasty and at a predetermined follow-up time of 30, 60, 90 or 120 days after the dilation. Measurements of the stenotic segments were expressed as minimal luminal diameter, and the adjacent nonstenotic segments were expressed as interpolated reference diameter (both in millimeters). A follow-up rate of 86% was achieved.
In the patients followed up at 30 and 60 days, there was no significant change in either the mean minimal luminal diameter or the mean reference diameter. However, at 90 and 120 days, there was significant deterioration in both the mean minimal luminal diameter (−0.37 and −0.42 mm, respectively) and the mean reference diameter (−0.17 and −0.26 mm, respectively), all of the changes being highly significant (p < 0.00001). The reference diameter is involved in the dilation process and may be subject to the same restenosis process that takes place in initially stenotic segments. Percent diameter stenosis measurements, which are conventionally used to express the change in the severity of a stenosis after angioplasty, will tend to underestimate the change when there is a simultaneous reduction in the reference diameter.
With the statistical assistance of Harald J. ten Katen and Gerrit A. van Es
- Received October 19, 1987.
- Revision received February 16, 1988.
- Accepted March 9, 1988.