Author + information
- Received June 13, 1988
- Revision received November 14, 1988
- Accepted December 15, 1988
- Published online June 1, 1989.
- Brian D. Hoit, MD, FACC∗∗,
- Michael Jones, MD, FACC†,
- Elling E. Eidbo†,
- William Elias‡ and
- David J. Sahn, MD, FACC∗,‡
- ↵∗Address for reprints: David J. Sahn, MD, Division of Pediatric Cardiology, University of California, San Diego Medical Center, 225 Dickinson Street, H814A, San Diego, California 92103.
To determine whether Doppler color flow mapping could be used to quantify changing levels of regurgitant flow and define the technical variables that influence the size of color flow images of regurgitant jets, nine stable hemodynamic states of mitral insufficiency were studied in four open chest sheep with regurgitant orifices of known size. The magnitude of mitral regurgitation was altered by phenylephrine infusion. Several technical variables, including the type of color flow instrument (Irex Aloka 880 versus Toshiba SSH65A), transducer frequency, pulse repetition frequency and gain level, were studied.
Significant increases in the color flow area, but not in color jet width measurements, were seen after phenylephrine infusion for each regurgitant orifice. For matched levels of mitral regurgitation, an increase in gain resulted in a 125% increase in color flow area. An increase in the pulse repetition and transducer frequencies resulted in a 36% reduction and a 28% increase in color flow area, respectively. Jet area for matched regurgitant volumes was larger on the Toshiba compared with the Aloka instrument (5.2 ± 3.1 versus 3.2 ± 1.2 CMZ, p < 0.05).
Color flow imaging of mitral regurgitant jets is dependent on various technical factors and the magnitude of regurgitation. Once these are standardized for a given patient, the measurement of color flow jet area may provide a means of making serial estimates of the severity of mitral insufficiency.
- Received June 13, 1988.
- Revision received November 14, 1988.
- Accepted December 15, 1988.