Author + information
- Received April 30, 1991
- Revision received July 10, 1991
- Accepted July 23, 1991
- Published online February 1, 1992.
- Julio E. Pérez, MD, FACC∗,
- Alan D. Waggoner, BA, RDMS,
- Benico Barzilai, MD, FACC,
- H.E. Melton Jr., PhD,
- James G. Miller, PhD and
- Burton E. Sobel, MD, FACC
- ↵∗Address for reprints: Julio E. Pérez, MD, Cardiovascular Division, Washington University School of Medicine, 660 South Euclid Avenue, Box 8086, St. Louis, Missouri 63110.
To provide an approach suitable for on-line analysis of ventricular function, a conventional two-dimensional ultrasound imaging system was modified to detect and track blood-tissue interfaces in real time based on their quantitative acoustic properties. This modification permitted on-line display of the left ventricular cavity area, fractional area change, volumes and ejection fraction on a beat by beat basis.
Images were obtained from 54 patients and 12 normal subjects with broad ranges of ventricular dimensions and systolic function. On-line measurements of cavity areas were compared with off-line measurements of cavity areas (analysis of videotaped conventional images). Left ventricular cavity areas measured on-line from short-axis views correlated closely with off-line views as did areas from apical views. On-line fractional area change correlated well with ejection fraction calculated off-line.
More than 70% of patients could be studied adequately with the approach developed. Thus, automatic boundary detection based on quantitative assessment of tissue acoustic properties permits on-line quantitation of ventricular cavity areas and indexes of function.
☆ This study was supported in part by Grants HL-17646 (SCOR in Coronary and Vascular Heart Disease) and HL40302 from the National Institutes of Health, Bethesda, Maryland.
- Received April 30, 1991.
- Revision received July 10, 1991.
- Accepted July 23, 1991.