Author + information
- Received February 24, 1993
- Revision received September 4, 1993
- Accepted October 15, 1993
- Published online March 15, 1994.
- William E. Sanders, MD,
- Robert A. Sorrentino, MD,
- Ruth Ann Greenfield, MD,
- Hossein Shenasa, MD,
- Mark E. Hamer, MD and
- J.Marcus Wharton, MD∗
- ↵∗Address for correspondence: J. Marcus Wharton, MD, Box 3816, Duke University Medical Center, Durham, North Carolina 27710.
Objectives. This study evaluates 1) the safety and efficacy of catheter delivery of radiofrequency current to eliminate sustained sinoatrial node reentrant tachycardia; 2) the incident of sinoatrial node reentrant tachycardia in the current group of patients undergoing electrophysiologic study for paroxysmal supraventricular tachycardia; and 3) the association of sinoatrial node reentrant tachycardia with other tachyarrhythmias.
Background. Sustained sinoatrial node reentrant tachycardia is an uncommon cause of paroxysmal supraventricular tachycardia that is reported to occur infrequently to conjunction with other arrhythmias. Although pharmacologic and surgical therapies are available, there is limited information with regard to catheter ablation of sinoatrial node reentrant tachycardia.
Methods. Ten patients with sustained sinoatrial node reentrant tachycardia underwent electrophysiologic study and radiofrequency current ablation. Patients were followed up for 9.2 ± 6.0 months.
Results. Of 343 consecutive patients referred for electrophysiotogic evaluation of paroxysmal supraventricular tachycardia, 11 (3.2%) wert found to have inducible sustained sinoatrial node reentrant tachycardia. Nine of the 11 patients had other associated arrhythmias, including atrioventricular (AY) node reentrant tachycardia (6 patients), AV reciprocating tachycardia (2 patients), ectopic atrial tachycardia (2 patients) and bundle branch reentrant tachycardia (1 patient). In 10 patients, direct ablation of sinoatrial node reentrant tachycardia was attempted and was successful in all (confidence interval for failure 0–0.26).Sinoatrial node reentrant tachycardia was eliminated with a median of four radiofrequency current application (range 1 to 10) at 20 to 30 W. Successful ablation site characteristics during sinoatrial node reentrant tachycardia included 1) atrial activation ≥35 ms (mean 44 ± 8 ms) before the onset of the surface P wave, 2) atrial activation ≥20 ms (mean 28 ± 6 ms) before the onset of high right atrial activation, and 3) significantly prolonged and fractionated electrograms (mean duration 87 ± 21 ms). No complications were encountered, and there have been no recurrences of sinoatrial node reentrant tachycardia.
Conclusions. Sinoatrial node reentrant tachycardia may be effectively and safely treated with radiofrequency current ablation at the site of earliest atrial activation.
☆ This study was supported in part by Grant HL-17670 from the National Institutes of Health, Bethesda, Maryland.
- Received February 24, 1993.
- Revision received September 4, 1993.
- Accepted October 15, 1993.