Author + information
- Received December 28, 1995
- Revision received April 4, 1996
- Accepted April 16, 1996
- Published online September 1, 1996.
- Katherine M. Detre, M.D., P.H.1,a,∗,†,
- Allan D. Rosen, M.S.a,∗,†,
- James E. Bost, PhDa,∗,†,
- Margaret E. Cooper, M.S.I.S., MEda,∗,†,
- Kim Sutton-Tyrrell, DrPHa,∗,†,
- Richard Holubkov, PhDa,∗,†,
- Richard J. Shemin, M.D.∗ and
- Robert L. Frye, M.D., F.A.C.C.†
- ↵1Address for correspondence: Dr. Katherine M. Detre, University of Pittsburgh, Department of Epidemiology, 130 DeSoto Street, A531 Crabtree Hall/GSPH, Pittsburgh, Pennsylvania 15261.
Objectives. To assess generalizability of the Bypass Angioplasty Revascularization Investigation (BARI), we conducted a separate study comparing revascularization in U.S. and BARI hospitals.
Background. The BARI trial is a multicenter investigation comparing initial revascularization with percutaneous transluminal coronary angioplasty and coronary bypass graft surgery in patients with symptomatic multivessel coronary disease.
Methods. All revascularization procedures during 5 consecutive workdays were surveyed at 75 U.S. hospitals offering coronary angioplasty and bypass surgery and at all BARI hospitals. Data collected were demographics, extent of disease and type of current and previous revascularization.
Results. At both U.S. and BARI hospitals, 57% of all revascularization procedures were coronary angioplasty and 43% were bypass surgery. The U.S. hospitals had m ore patients with single-vessel disease, acute myocardial infarction and primary procedures. Other characteristics were similar. The majority of revascularization procedures were angioplasty for single-vessel disease (U.S. 32% vs. BARI 25%) and bypass surgery for triple-vessel disease (U.S. 31% vs. BARI 31%). Overall, the choice between bypass surgery and angioplasty was similar in BARI and U.S. hospitals (adjusted odds ratio [OR] 1.0, p = 0.914). However, older patients were more likely and younger patients less likely to undergo bypass surgery in BARI versus U.S. hospitals (older patients: adjusted OR 1.6, p = 0.031; younger patients: adjusted OR 0.6, p = 0.028). The BARI protocol would have excluded 65% of all candidates for revascularization, for whom indications already exist for angioplasty or bypass surgery, and another 23%, for whom angioplasty would be contraindicated for individual lesions.
Conclusions. Patients undergoing coronary revascularization in BARI and U.S. hospitals were generally similar, as was the choice between types of revascularization. Results from the BARI trial apply to ∼300 (12%) candidates for coronary revascularization/workday.
☆ This study was supported by Grant HL38610 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
- Received December 28, 1995.
- Revision received April 4, 1996.
- Accepted April 16, 1996.