|Prevalence in Infancy (per 1,000)||Estimated Prevalence of Simple Lesions in Adulthood (per 1,000)|
↵∗ Most ventricular septal defects (VSDs) are closed by adulthood and are no longer a problem (i.e., the patients no longer have a “lesion”).
↵† Most patent ductus arteriosi (PDAs) close spontaneously or are closed in childhood, and therefore remain in the “simple” category.
↵‡ Most atrial septal defects (ASDs) are closed in childhood, and therefore remain in the “simple” category.
↵§ Most pulmonary stenoses (PS) remain in the “simple” category; some will become moderate or severe; and some will develop pulmonary regurgitation, and therefore be defined as “moderately complex.”
↵legend AS = aortic stenosis.