|• High-risk treadmill score (score ≤-11)|
|• Stress-induced large perfusion defect (particularly if anterior)|
|• Stress-induced perfusion defects of moderate size|
|• Stress-induced multiple perfusion defect with LV dilation or increased lung uptake (thallium-201)|
|• Echocardiographic wall motion abnormality (involving >2 segments) developing at a low dose of dobutamine (≤10 mg·kg−1·min−1) or at a low heart rate (120 bpm)|
|• Stress echocardiographic evidence of extensive ischemia|
↵legend Adapted with permission from Gibbons RJ, Chatterjee K, Daley J, et al. ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina. J Am Coll Cardiol 1999;33:2092–197.