Author + information
- Andrew P Davie, MDa
Lagerqvist et al. (1)are to be congratulated for their recent elaboration of the findings of FRISC II. I am sure we are all very interested in reiteration of the fact that women do not benefit as much as men from an early invasive strategy. I must take issue, however, with one suggestion that they make. They speculate that women might have done less well (in fact, women appear to have done non-significantly worse) with an invasive strategy because of more advanced age, more frequent diabetes and more frequent previous myocardial infarctions (MIs). If this were true, then these groups themselves would have been expected to do less well with an invasive strategy. In fact, all these groups—over age 65 (risk ratio [RR] 0.59), diabetics (RR 0.62) and previous MIs (RR 0.86)—appeared to benefit from an invasive strategy (2). The investigators will surely have to look elsewhere for an explanation of their tantalizing findings.
- American College of Cardiology Foundation