Author + information
- Received November 18, 1983
- Revision received March 19, 1984
- Accepted April 6, 1984
- Published online September 1, 1984.
- Ioannis P. Panidis, MD*,1,
- Jian-Fang Ren, MD1,
- Morris N. Kotler, MD, FACC1,
- Gary S. Mintz, MD, FACC1,
- Eldred D. Mundth, MD, FACC1,
- Inder P. Goel, MD, FACC1 and
- John Ross, RCPT1
- ↵*Address for reprints: Ioannis Panidis, MD, Non-invasive Cardiac Laboratory, 230 North Broad Street, Philadelphia, Pennsylvania 19102.
One hundred twenty-six patients with a St. Jude valve prosthesis were followed up clinically and studied by combined M-mode echocardiography and phonocardiography. Fifty patients underwent aortic valve replacement, 58 underwent mitral valve replacement and 18 underwent a combination of the two. The early postoperative mortality rate was 8% for aortic, 6.9% for mitral and 6% for combined valve replacement. Followup ranged from 2 to 46 months (mean ± SD 28 ± 9). The late postoperative mortality rate was 5%; in patients who survived, improvement in New York Heart Association functional class occurred in 97%. Major thromboembolic events occurred in two patients and antico-agulation-related complications occurred in three patients.
Valve-related complications occurred in 14 patients and included bacterial endocarditis (6 patients), para-valvular leak (5 patients), severe hemolysis (1 patient), thrombosis of valve (1 patient) and possible mechanical valve failure (1 patient). In 7 of these 14 patients, repeat surgery was required and 5 patients survived. Abnormal echocardiography findings in these seven patients included a shortened aortic closure (A2) to mitral valve opening interval, increased left atrial and left ventricular size and initial diastolic rounding of the St. Jude valve motion in the patient with the thrombosed valve.
It is concluded that the St. Jude valve prosthesis is associated with favorable functional results and a low complication rate for a mean follow-up period of 28 months. Combined M-mode echocardiography and phonocardiography may be useful in assessing patients with suspected complications related to the St. Jude cardiac valve.
- Received November 18, 1983.
- Revision received March 19, 1984.
- Accepted April 6, 1984.
- American College of Cardiology Foundation