Author + information
- Jalal K Ghali, MDa ()
I read with great interest the study by Horwich et al. (1)on the association of anemia with poor prognosis in advanced heart failure. The investigators observed that mortality decreased in linear fashion as hemoglobin level increased without excess mortality at the highest hemoglobin level. However, hemoglobin level >17 g/dl was seen in only 3% of men and 1% of women. Thus, the small number of patients at high hemoglobin level could have limited the investigators’ ability to observe a U-shaped relationship.
The percentage of patients with chronic obstructive lung disease who are the most likely candidates to have high hemoglobin were not listed in the report. I would appreciate the investigators’ comments.
- American College of Cardiology Foundation