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Malouf et al. (1)have presented data in an uncommon but clinically important subgroup of patients with severe aortic stenosis and severe pulmonary hypertension. In their study, one subgroup of patients had aortic valve replacement and another was treated medically. The data are very interesting and important.
However, to understand fully the study groups and their outcomes, the investigators need to present additional information about the two subgroups:
1. How was left ventricular ejection fraction measured?
2. What was the actual calculated pulmonary artery systolic pressure (PASP) (mean ± SD, and range)?
3. What were the number and percentage of patients who underwent selective coronary arteriography? Of those who underwent coronary arteriography, what were the number and percentage who had significantly obstructive coronary artery disease? Also, did all patients with significantly obstructive coronary artery disease have coronary bypass graft surgery? It should be noted that the mean patient age was 78 ± 8 years.
4. What was the five-year survival, including operative mortality (mean ± SE) and the p value for the difference in survival?
These investigators are to be congratulated on this valuable study in a group of patients in whom additional data were needed.
- American College of Cardiology Foundation