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I have read the interesting letter by Profs. Nadar and Lip. Their speculation on the results of our study adds an additional interpretation of our data. However, our study focused on cardiac and vascular remodeling rather than on prothrombotic factors; thus, because we did not analyze whether isolated systolic hypertension was associated with direct evidence of a prothrombotic state we cannot provide substantive comments on the interesting speculations of Profs. Nadar and Lip.
- American College of Cardiology Foundation