Author + information
- Mathew Maurer, MD,
- Daniel Spevack, MD,
- Daniel Burkhoff, MD and
- Itzhak Kronzon, MD, FACC, FACP⁎ ()
- ↵⁎Noninvasive Cardiology New York University School of Medicine 560 First Avenue New York, NY 10016
We thank Dr. Sanderson for his interest in our study (1). As more investigators take a fresh look at the matter of heart failure in the setting of normal ejection fraction (HFNEF), the greater the number of questions that are being raised as to whether this condition is always due to diastolic dysfunction. Although currently an unpopular point of view, an increasing amount of data indicate that HFNEF and the Doppler echocardiographic changes found in this condition can occur without diastolic dysfunction as defined in the classical sense. Dr. Sanderson is one of many such investigators, and we thank him for coming forward to express these sentiments. Many abnormalities are being identified in subsets of HFNEF patients, including those noted by Dr. Sanderson. It will be of great interest to follow how these are unraveled to reveal the primary mechanisms underlying HFNEF so that specific, more effective treatments can be developed. What is most needed at the present time is that the cardiology community adopt an open mind with enhanced receptivity to new ideas about a very important health problem.
- American College of Cardiology Foundation