|Variable||Univariate Analysis p Value†||Multivariate Analysis p Value§||Multivariate Analysis Hazard Ratio (95% CI)|
|NYHA functional class (III to IV)||0.0001||0.022||3.07 (1.17–8.05)|
|LV outflow obstruction||0.022||0.146||1.68 (0.83–3.40)|
|Atrial fibrillation||0.0001||<0.001||4.33 (1.94–9.64)|
|LV wall thickness (mm)||0.004||<0.001||1.12 (1.05–1.20)|
|LV diastolic diameter (mm)||0.634||0.93||‡|
|Left atrial size (mm)||0.0001||0.61||‡|
|Family history of sudden death||0.422||0.80||‡|
Abbreviations as in Tables 1 and 2.
↵⁎ The subgroups for each variable were as follows: age was grouped in four classes, <20, 20 to 39, 40 to 59, and ≥60 years. New York Heart Association functional class was grouped in two classes: I to II vs III to IV. Wall thickness was grouped in four classes, <15, 15 to 19, 20 to 24, 25 to 29, and ≥30 mm.
↵† Estimated from a Cox model in which the covariates were individually included one at a time.
↵§ Estimated from the final Cox model obtained by means of a step-down procedure, based on the likelihood ratio test, starting from the initial model in which all covariates were included.
↵‡ Excluded from the final model.