|Variable||Hazard Ratio (95% CI)||p Value|
|Interaction of LV outflow obstruction with|
|NYHA functional class||0.07 (0.01–0.70)||0.024|
|LV wall thickness||0.92|
|Prognostic power of|
|LV obstruction in NYHA functional class I to II patients||2.38 (1.12–5.09)||0.025|
|LV obstruction in NYHA functional class III to IV patients||1.18 (0.57–2.43)||0.66|
|Presence or development of NYHA functional class III to IV in patients with or without LV obstruction||7.90 (3.72–16.79)||<0.001|
A multivariate Cox model was fitted to the data, and the potential influence of other variables on the prognostic power of the outflow gradient was investigated by introducing into the model the appropriate interaction terms. *All p values are derived from the likelihood ratio test. For variables with more than two groups, p values refer to the test of the trend of increasing (or decreasing) risk across the categories of the variable.
Abbreviations as in Tables 1 and 2.