Author + information
- Received June 13, 2005
- Revision received February 23, 2006
- Accepted February 28, 2006
- Published online July 18, 2006.
- Steven B. Feinstein, MD, FACC⁎ ()
- ↵⁎Reprint requests and correspondence:
Dr. Steven B. Feinstein, Rush Presbyterian St. Luke’s Medical Center, Medicine, 1750 West Harrison, 1015 Jelke, Chicago, Illinois 60612.
Cardiovascular disease is associated with the aging of the population, obesity, metabolic syndrome, and diabetes. Therefore, it is important to develop non-invasive imaging systems to detect “at-risk” populations. New data suggest that contrast-enhanced ultrasound (CU) imaging of the carotid arteries enhances luminal irregularities (i.e., ulcers and plaques), improves near-wall, carotid intima-media thickness, and uniquely permits direct, real-time visualization of neovasculature of the atherosclerotic plaque and associated adventitial vasa vasorum. With continued clinical investigation, CU imaging of the carotid artery may afford an effective means to non-invasively identify atherosclerosis in “at-risk” populations while providing new standard for therapeutic monitoring.
The author has received speaking honorarium from KOS Pharmaceutical, Takeda Pharmaceutical, and GE Health Care, and a research grant from Takeda Pharmaceutical.
- Received June 13, 2005.
- Revision received February 23, 2006.
- Accepted February 28, 2006.
- American College of Cardiology Foundation
- Understanding the role of vasa vasorum and plaque neovascularization in the development of atherosclerosis
- CU carotid imaging for identification of surrogate markers of atherosclerosis
- CU carotid imaging for identification of regression of adventitial vasa vasorum
- Neovascular nourishment of tumors