|Relative Risk||95% CI||Chi-Square||p Value|
|Family history of premature CAD||0.63||0.51–0.78||19||<0.0001|
|Coronary calcium results|
|CAC score categories of 1–10, 11–100, 101–299, 300–399, 400–699, 700–999, ≥1,000 vs. 0||1.68||1.63–1.74||1,181||<0.0001|
|Average lesion extent|
|CAD extent (/vessel)||2.69||2.35–3.08||270||<0.0001|
Description of CAC univariable models: 1) CAC score categories of 1–10, 11–100, 101–299, 300–399, 400–699, 700–999, ≥1,000 vs. 0: This model provides a univariable risk ratio for each category of increasing CAC extent (n = 7 categories) as compared with a CAC score of 0. Individual risk ratio were not analyzed, because additional analyses within the results provides risk-adjusted risk ratios. 2) For the LM, circumflex, RCA, and LAD lesions, this is an analysis of the total number of lesions within each vascular territory; as such, the risk ratio reveals the increase for every number of lesions when compared with no lesions in that vascular territory. 3) For the average lesion extent univariable analysis, this examines the average vascular territory score/lesion identified within the LM, circumflex, RCA, and LAD areas. Thus, the risk ratio reveals the x-fold increase in mortality for a given average lesion extent. 4) The CAD extent analysis includes the number of vascular territories with scores ≥100.
CAC = coronary artery calcium; CAD = coronary artery disease; CI = confidence interval; LAD = left anterior descending territory; LM = left main territory; RCA = right coronary artery territory.