Author + information
- Received October 26, 2007
- Accepted October 31, 2007
- Published online March 11, 2008.
- Elad I. Levy, MD⁎,†,‡,⁎ (, )
- J. Mocco, MD, MS⁎,‡,
- Rodney M. Samuelson, MD⁎,‡,
- Robert D. Ecker, MD⁎,‡,
- Babak S. Jahromi, MD, PhD⁎,‡ and
- L. Nelson Hopkins, MD⁎,†,‡
- ↵⁎Reprint requests and correspondence:
Dr. Elad I. Levy, University at Buffalo Neurosurgery, Millard Fillmore Gates Hospital, 3 Gates Circle, Buffalo New York 14209.
Extracranial carotid artery disease accounts for approximately 25% of ischemic strokes. Although carotid endarterectomy (CEA) is the established gold standard for carotid revascularization, carotid artery angioplasty and stenting (CAS) is continually developing into a safer and more efficacious method of stroke prevention. Embolic protection, improving stent designs, and ever-increasing surgeon experience are propelling CAS towards equipoise with and possible superiority to CEA. One multicenter randomized trial and several nonrandomized registries have successfully established CAS as an accepted treatment for high-risk patients. Clinicians must strive to perform well-designed clinical trials that will continue to aid understanding and improve application of both endovascular and open techniques for extracranial carotid revascularization. We review the data published to date regarding the indications for and recent developments in the use of CAS.
Dr. Hopkins receives grant support from Boston Scientific, Cordis, and Micrus Endovascular and honoraria from Bard, Boston Scientific, Cordis, and Medsn; owns stock in APW Holding, Inc., Boston Scientific, and Micrus Endovascular; is a consultant for Abbott, Bard, Boston Scientific, and Cordis; and is a board member, trustee, or officer with Access Closure, market Rx, and Micrus Endovascular. Dr. Levy receives grant support and honoraria from Boston Scientific and Cordis, patent royalties from Zimmer Spine, and financial support from Abbott Vascular and ev3 for carotid stent training. Dr. Mocco is supported by a research grant from the Brain Aneurysm Foundation.
- Received October 26, 2007.
- Accepted October 31, 2007.
- American College of Cardiology Foundation