|2004 STEMI Guideline Recommendation||2007 STEMI Focused Update Recommendation||Comments|
|Facilitated PCI might be performed as a reperfusion strategy in higher-risk patients when PCI is not immediately available and bleeding risk is low. (Level of Evidence: B)||1. Facilitated PCI using regimens other than full-dose fibrinolytic therapy might be considered as a reperfusion strategy when all of the following are present: a. Patients are at high risk, b. PCI is not immediately available within 90 minutes, and c. Bleeding risk is low (younger age, absence of poorly controlled hypertension, normal body weight). (Level of Evidence: C)||Modified recommendation (changed LOE and text)|
|1. A planned reperfusion strategy using full-dose fibrinolytic therapy followed by immediate PCI may be harmful. (Level of Evidence: B)||New recommendation|
LOE indicates level of evidence; PCI, percutaneous coronary intervention, and STEMI, ST-elevation myocardial infarction.