|Translational Step||Key Aspects of Translational Step||Reperfusion for STEMI|
|1||Activity to test what care works:||Randomized clinical trials of fibrinolysis and catheter-based therapies|
|2||Activities to test who benefits from providing care:||Registries such as the joint ACC/AHA ACTION-GWTG Registry|
|3||Activities to test how to deliver high-quality care reliably and in all settings:||ACC D2B Alliance|
|AHA Mission: Lifeline|
Adapted from information in Dougherty and Conway (28).
ACC = American College of Cardiology; ACTION = Acute Coronary Treatment and Intervention Outcomes Network; AHA = American Heart Association; D2B = door-to-balloon; GWTG = Get With the Guidelines; other abbreviation as in Table 1.