Author + information
- Received August 25, 2008
- Revision received March 25, 2009
- Accepted April 17, 2009
- Published online November 17, 2009.
- ↵*Reprint requests and correspondence:
Dr. John B. Gordon, San Diego Cardiac Center, 3131 Berger Street, Suite 200, San Diego, California 92123
Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric age group in developed countries. The majority of patients with KD appear to have a benign prognosis, but a subset of patients with coronary artery aneurysms are at risk for ischemic events and require lifelong treatment. In the 4 decades that have passed since the initial recognition of KD, the number of patients reaching adulthood has continued to grow. Adult cardiologists will be increasingly involved in the management of these patients. Currently, there are no established guidelines for the evaluation and treatment of adult patients who have had KD. We review here the current literature that may be helpful to clinicians who care for adults who experienced KD in childhood.
This work supported in part by a grant from the National Institutes of Health, Heart, Lung, Blood Instituteto Dr. Burns (RO1-HL69413). Masato Takahashi, MD, served as Guest Editor for this article.
- Received August 25, 2008.
- Revision received March 25, 2009.
- Accepted April 17, 2009.
- American College of Cardiology Foundation
- Epidemiology and Clinical Aspects of Acute KD
- Cardiovascular Sequelae of KD in Adults
- Missed KD Presenting in Adulthood
- Endothelial-Cell Dysfunction and Arterial Wall Injury
- Identifying the Adult With Possible Antecedent KD
- Management of the Adult With Antecedent KD