|Patient Risk Level||Recommendation|
|AHA risk level 1 and 2||Consider noninvasive testing every 3–4 yrs.*No medical therapy.|
|AHA risk level 3, 4, 5 without symptoms||Evaluate every 4–6 months with noninvasive testing and angiography every 2–3 years. Treat with low-dose aspirin.|
|AHA risk level 3, 4, 5 with symptoms||Evaluate every 3–4 months with noninvasive testing and angiography as needed. Treat with low-dose aspirin; other medications as dictated by the cardiovascular status.|
Data from the Japanese Circulation Society (83).
AHA = American Heart Association.
↵* Noninvasive testing: exercise testing, nuclear imaging studies, Holter monitor, transesophageal echocardiogram, magnetic resonance angiography, and computed tomography angiogram.