Journal of the American College of Cardiology
Acute Coronary Syndromes
A Risk Score to Predict Bleeding in Patients With Acute Coronary Syndromes
Roxana Mehran, Stuart J. Pocock, Eugenia Nikolsky, Tim Clayton, George D. Dangas, Ajay J. Kirtane, Helen Parise, Martin Fahy, Steven V. Manoukian, Frederick Feit, Magnus E. Ohman, Bernard Witzenbichler, Giulio Guagliumi, Alexandra J. Lansky and Gregg W. Stone
Table 5
Table 5
Hierarchical Incidence of Non–CABG-Related Major Bleeding Within 30 Days
| ACUITY (n = 13,819) | HORIZONS (n = 3,602) | Total (n = 17,421) | |
|---|---|---|---|
| TIMI-defined major bleed | 204 (1.5%) | 84 (2.3%) | 288 (1.7%) |
| Non-TIMI major bleed with blood transfusion | 190 (1.4%) | 42 (1.2%) | 232 (1.3%) |
| Non-TIMI major bleed without blood transfusion | 172 (1.2%) | 98 (2.7%) | 270 (1.5%) |
| Large hematoma only* | 124 (0.9%) | 14 (0.4%) | 138 (0.8%) |
| Total | 690 (5.0%) | 238 (6.6%) | 928 (5.3%) |
Each patient is represented only once according to their most severe bleed. In the ACUITY trial, 46 Thrombolysis In Myocardial Infarction (TIMI) bleeds were not included under the definition for major bleed.
Abbreviations as in Table 1.
↵* Hematomas are not included in earlier analysis of major bleeds.
Advertisement