Author + information
- Received April 23, 2009
- Revision received May 28, 2009
- Accepted June 9, 2009
- Published online January 19, 2010.
- ↵*Reprint requests and correspondence:
Dr. Morton J. Kern, Division of Cardiology, University of California, Irvine, 333 West City Tower Drive, Suite 400, Room 407, Orange, California 92868-4080
Over the last 15 years, the use of invasive coronary physiology in the catheterization laboratory has demonstrated favorable outcomes for decision making in patients with intermediate single-vessel stenoses, complex bifurcation and ostial branch stenoses, multivessel coronary artery disease, and left main stenoses. A recent large multicenter study (FAME [FFR versus Angiography for Multivessel Evaluation]) found that a physiologically-guided approach was superior to the standard angiographically-guided approach for percutaneous revascularization in patients with multivessel coronary artery disease. This review addresses selected pertinent concepts and studies supporting the integration of coronary physiology in the catheterization laboratory for optimal patient outcomes.
Dr. Kern has served as a speaker for Volcano Therapeutics and St. Jude Medical, manufacturers of pressure guidewires. Dr. Samady has served as a speaker for Radi Medical/St. Jude Medical and has received a research grant from Volcano Therapeutics.
- Received April 23, 2009.
- Revision received May 28, 2009.
- Accepted June 9, 2009.
- American College of Cardiology Foundation
- Rationale for Coronary Physiology in the Cath Lab
- Fractional Flow Reserve (FFR) Theory and Measurement
- Validation and Threshold of Ischemia
- Outcome of Using FFR for Intermediate Lesions
- Multivessel CAD
- Left Main Stenosis
- FFR and Ostial Branch Assessment
- FFR and CABG Conduit Patency
- FFR and Acute Coronary Syndrome (ACS)