|First Author (Ref. #)||Origin||Characteristics of CAD||Enrollment||No. of Subjects (% Women)||Follow-Up (Months), Mean ± SD||Deaths, n||Main Results|
|Kanaya et al. (14)||United States||MI, CABG, PCI, or angiographic occlusion ≥50% of ≥1 coronary arteries||1993–1994||2,739 (100%)||81.6 ± 4.8||498||Increasing WC was directly related to higher mortality, whereas BMI exhibited a “U-shaped” association with mortality.|
|Kragelund et al. (15)||Denmark||Acute myocardial infarction||1990–1992||6,676 (33%)||73.8 ± 57.5||4,534||Men in the upper quartile of WHR had increased mortality compared with the lowest quartile, but the association was not significant in women. There was no association of BMI with mortality.|
|Zeller et al. (16)||France||Acute myocardial infarction||2001–2007||2,229 (27%)||Median 12 months||301||WC and BMI were not independent predictors of death, but subjects with normal BMI and high WC had increased mortality.|
|Lee et al. (18)||Korea||STEMI||2005–2006||3,734 (26%)||6.6 ± 1.0||175||Increasing WHR was directly associated with higher mortality, whereas increasing BMI was inversely associated with mortality.|
|Mayo Clinic Cardiovascular Rehabilitation cohort||Rochester, MN||MI, CABG, PCI, or known history of CAD||1993–2007||1,038 (20%)||104 ± 44||188||Unpublished data|
BMI = body mass index; CABG = coronary artery bypass grafting; CAD = coronary artery disease; MI = myocardial infarction; PCI = percutaneous coronary intervention; STEMI = ST-segment elevation myocardial infarction; WC = waist circumference; WHR = waist-hip ratio.