|Stroke diagnostic criteria|
|Rapid onset of a focal or global neurological deficit with at least one of the following: change in level of consciousness, hemiplegia, hemiparesis, numbness or sensory loss affecting one side of the body, dysphasia or aphasia, hemianopia, amaurosis fugax, or other neurological signs or symptoms consistent with stroke|
|Duration of a focal or global neurological deficit ≥24 h; OR <24 h, if therapeutic intervention(s) were performed (e.g. thrombolytic therapy or intracranial angioplasty); OR available neuroimaging documents a new hemorrhage or infarct; OR the neurological deficit results in death|
|No other readily identifiable nonstroke cause for the clinical presentation (e.g., brain tumor, trauma, infection, hypoglycemia, peripheral lesion, pharmacological influences)⁎|
|Confirmation of the diagnosis by at least one of the following:|
|Neurology or neurosurgical specialist|
|Neuroimaging procedure (MR or CT scan or cerebral angiography)|
|Lumbar puncture (i.e., spinal fluid analysis diagnostic of intracranial hemorrhage)|
|Transient ischemic attack:|
|New focal neurological deficit with rapid symptom resolution (usually 1 to 2 h), always within 24 h|
|Neuroimaging without tissue injury|
|Stroke: (diagnosis as above, preferably with positive neuroimaging study)|
|Minor—Modified Rankin score <2 at 30 and 90 days†|
|Major—Modified Rankin score ≥2 at 30 and 90 days|
CT = computed tomography; MR = magnetic resonance.
↵⁎ Patients with non-focal global encephalopathy will not be reported as a stroke without unequivocal evidence based upon neuroimaging studies.
↵† Modified Rankin score assessments should be made by qualified individuals according to a certification process. If there is discordance between the 30 and 90 day Modified Rankin scores, a final determination of major versus minor stroke will be adjudicated by the neurology members of the clinical events committee.