Author + information
- Received February 20, 2011
- Revision received August 9, 2011
- Accepted August 21, 2011
- Published online November 29, 2011.
- Tze-Fan Chao, MD*,†,
- Yenn-Jiang Lin, MD*,†,
- Hsuan-Ming Tsao, MD†∥,
- Chin-Feng Tsai, MD¶,
- Wei-Shiang Lin, MD‡,
- Shih-Lin Chang, MD*,†,
- Li-Wei Lo, MD*,†,
- Yu-Feng Hu, MD*,†,
- Ta-Chuan Tuan, MD*,†,
- Kazuyoshi Suenari, MD*,#,
- Cheng-Hung Li, MD*,†,
- Beny Hartono, MD*,
- Hung-Yu Chang, MD§,
- Kibos Ambrose, MD*,
- Tsu-Juey Wu, MD†,¶ ( and )
- Shih-Ann Chen, MD*,†,* ()
- ↵*Reprint requests and correspondence:
Drs. Shih-Ann Chen and/or Tsu-Juey Wu, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, Taiwan
Objectives This study aimed to evaluate whether CHADS2 and CHA2DS2-VASc scores are useful for risk stratification in patients after catheter ablation of atrial fibrillation (AF).
Background AF is associated with increased risk of cardiovascular events. However, limited data are available on the predictors of adverse events in patients with AF after catheter ablation.
Methods A total of 565 patients with AF who underwent catheter ablation were enrolled in the study. The clinical endpoint was occurrence of thromboembolic events (ischemic stroke, transient ischemic attack, peripheral embolism, or pulmonary embolisms) or death during follow-up after catheter ablation.
Results During a follow-up of 39.2 ± 22.6 months, 27 patients (4.8%) experienced adverse events. Both the CHADS2 and CHA2DS2-VASc scores were useful predictors of events in separate multivariate models. The areas under the receiver-operator characteristic curves based on the CHADS2 and CHA2DS2-VASc scores in predicting events were 0.785 and 0.830, respectively. Although the difference did not reach statistical significance (p = 0.116), the CHA2DS2-VASc score could be used to further stratify the patients with CHADS2 scores of 0 or 1 into 2 groups with different event rates (7.1% vs. 1.1%, p = 0.003) at a cutoff value of 2.
Conclusions The CHADS2 and CHA2DS2-VASc scores are useful predictors of adverse events after catheter ablation of AF.
The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received February 20, 2011.
- Revision received August 9, 2011.
- Accepted August 21, 2011.
- American College of Cardiology Foundation