|2012 Focused Update Recommendations||2012 Comments|
|1. Medical treatment in the acute phase of UA/NSTEMI and decisions on whether to perform stress testing, angiography, and revascularization should be similar in patients with and without diabetes mellitus (55,72,81,147). (Level of Evidence: A)||2007 recommendation remains current.|
|1. For patients with UA/NSTEMI and multivessel disease, CABG with use of the internal mammary arteries can be beneficial over PCI in patients being treated for diabetes mellitus (148). (Level of Evidence: B)||2007 recommendation remains current.|
|2. PCI is reasonable for UA/NSTEMI patients with diabetes mellitus with single-vessel disease and inducible ischemia (55). (Level of Evidence: B)||2007 recommendation remains current.|
|3. It is reasonable to use an insulin-based regimen to achieve and maintain glucose levels less than 180 mg/dL while avoiding hypoglycemia⁎ for hospitalized patients with UA/NSTEMI with either a complicated or uncomplicated course (149–152). (Level of Evidence: B)||2011 recommendation remains current.|
CABG indicates coronary artery bypass graft; PCI, percutaneous coronary intervention; and UA/NSTEMI, unstable angina/non–ST-elevation myocardial infarction.
↵⁎ There is uncertainty about the ideal target range for glucose necessary to achieve an optimal risk-benefit ratio.