|Parameter||n||Age at Diagnosis||p Value|
|Age at first CAD diagnosis||9,275||–1.581||0.295||8.2 × 10–8|
|Age at first MI||5,148||–0.918||0.416||0.028|
|Age at first CAD diagnosis for MI cases||5,148||–1.334||0.400||0.00085|
|Age at first CAD diagnosis||333||–3.541||2.521||0.16|
|Age at first MI||185||–2.221||3.249||0.50|
|Age at first CAD diagnosis for MI cases||185||–6.009||3.159||0.059|
MI = myocardial infarction. Other abbreviations as in Table 2.
↵⁎ Linear regression coefficients (β) with corresponding standard errors (SE) and p values, assuming additive allelic effects. The model included sex as a covariate. In addition, study site (Iceland/Atlanta) was a covariate in the model when analyzing those of European ancestry.