Author + information
- Valentina Parisi,
- Gennaro Galasso,
- Claudio De Lucia,
- Raffaele Piccolo,
- Giuseppe Rengo,
- roberta de rosa,
- Grazia Daniela Femminella,
- Dario Leosco,
- Gennaro Pagano,
- Nicola Ferrara and
- Federico Piscione
Speckle tracking echocardiography accurately describes left ventricular (LV) deformation. We tested the ability of three dimensional strain (3DS) in detecting resting LV dysfunction in patients with suspected coronary artery disease (CAD).
Twenty pts, with normal global and regional LV function assessed by 2D-echo and stress-induced LV ischemia, underwent a complete echocardiographic examination. Global and regional 3DS was evaluated. The strain value of the17 LV segments was assessed and regional strain was expressed by mean strain value of those segments assigned to each of the 3 main coronary-related myocardial distribution territories. Pts were then referred to coronary angiography. A coronary lesion greater than 75% of lumen diameter was considered significant.
Eleven pts had significant CAD (Group I, mean age:62±7), while 9 pts did not show significant CAD (Group II, mean age 60±9). Group I showed a reduced 3D global longitudinal, circumferential, area and radial strain compared to Group II. Reduction of regional 3DS was significantly associated with presence of significant CAD in the corresponding coronary artery (Table).
Alterations of LV deformation detected by global 3DS are related to significant CAD. Moreover, there is a good correlation between regional 3DS and the diseased coronary district.
|Regional Strain||LAD (Group I)||LAD (Group II)||LCx (Group I)||LCx (Group II)||RCA (Group I)||RCA (Group II)|
|Longitudinal||−9,8 +/− 3,6 *||−13,7 +/−3||−8,6 +/− 3,8 *||−13,1 +/− 4,8||−9,6 +/− 3,1||−10,1 +/− 2,2|
|Circumferential||−7,1 +/− 2,4 *||−15,1 +/−3||−11,5 +/− 1,9 *||−14,6 +/− 3,6||−19,3 +/− 6,6 *||−26,8 +/− 7|
|Area||−15,1 +/− 3,6 *||−25,1 +/− 3,4||−17,5 +/− 5,2||−21,2 +/− 3,9||−19,3 +/− 6,6 *||−26,8 +/− 7|
|Radial||21,6 +/− 6 *||38,1 +/− 8||24,7 +/− 4,7 *||37,5 +/− 5,3||25,7 +/− 11 *||40,6 +/− 12|
↵* p<0,005 vs Group II. LAD:Left Anterior Descending Coronary Artery; LCx:Left Circumflex Coronary Artery; RCA:Right Coronary Artery
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Imaging: Echocardiographic Imaging of Patients with CAD: II
Abstract Category: 18. Imaging: Echo
Presentation Number: 1266-319
- 2013 American College of Cardiology Foundation