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We hypothesized that assessment of 3D wall motion tracking method is possible to detect small change of systolic function and myocardial risk area by 3D adenosine stress echocardiography inpatients with ischemic heart disease (IHD).
We examined 39 vessel areas by 3D adenosine stress echocardiography in IHD patients. 3D full volume images were acquired (iE33TM and X5-1TM, Phillips Healthcare) at rest and during adenosine infusion. We assessed the change of 3D-, circumferential-, longitudinal and radial strains by 4D LV-Analysis© (TomTec). All 16 segments of myocardium were divided to 3 vessels area according to territory of coronary arteries. Each vessels area was defined as ischemia when the decreasing area of strain appeared after adenosine infusion, and compared the finding of coronary angiography.
There was significant coronary stenosis (≥ 75%) in 16 of 39 vessels. The decreasing area of strain by adenosine was consistent with risk area (Figure). The ability of diagnosis for coronary stenosis was follows: 3D-strain: sensitivity 62.5%, specificity 82.6%; c-strain: sensitivity 68.8%, specificity 95.7%; l-strain: sensitivity 43.8%, specificity 87.0%; r-strain: sensitivity 43.8%, specificity 87.0%. The most useful index to detect ischemia was circumferential strain.
3D adenosine stress echocardiography will be a potential diagnostic tool and the parametric imaging of circumferential strain is useful to detect risk area in patients with IHD.
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Imaging: Echocardiographic Imaging of Patients with CAD: I
Abstract Category: 18. Imaging: Echo
Presentation Number: 1267-325
- 2013 American College of Cardiology Foundation