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We aimed to assess the agreement between late enhancement 64-slice computed tomography (LE MSCT) and late enhancement magnetic resonance imaging (LE MRI) in evaluation of myocardial viability and to compare these techniques for predicting functional recovery after acute myocardial infarction (AMI).
83 patients with AMI treated with successful primary coronary angioplasty were included in the study. 7-10 days after AMI patients underwent LE MSCT, LE MRI and transthoracic echocardiography (TTE) with assessment of left-ventricular systolic function. The thickness of late enhancement region (LE) was assessed semi-quantitatively in 17 segments of the left ventricle using 5-grade scale. One year after AMI all patients underwent control TTE.
The assessment of LE thickness on LE MSCT and LE MRI was concordant in 90,3% of segments (weighted kappa 0,862). Baseline TTE revealed 254 akinetic or dyskinetic segments, 43,7% of which recovered function after 1 year. The areas under ROC curves for LE MSCT and LE MRI for predicting segmental functional recovery were not significantly different (0,709 and 0,737, respectively; p=0,233). Moreover, the accuracy of criteria based on LE thickness for predicting functional recovery did not differ significantly between MSCT and MRI (p=NS; Table 1).
The agreement between LE MSCT and LE MRI in the assessment of infarct size is very good. Both methods offer similar prognostic value for predicting regional functional recovery after AMI.
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Multimodality Imaging in Cardiomyopathy
Abstract Category: 20. Imaging: CT/Multimodality
Presentation Number: 1316-366
- 2013 American College of Cardiology Foundation