Author + information
- Mads K. Ersboll,
- Mads J. Andersen,
- Nana Valeur,
- Ulrik M. Mogensen,
- Homa Waziri,
- Jacob E. Moller,
- Christian Hassager,
- Peter Sogaard and
- Lars Kober
Peak atrial longitudinal strain (PALS) during the reservoir phase has been proposed as a measure of LA function. However, no studies have assessed the interrelation of PALS and LV longitudinal strain (GLS) in large scale populations in regard to prognosis.
We prospectively included 843 patients (mean age 62.1± 11.8, 74% male) with acute myocardial infarction and measured GLS, LA volumes and PALS within 48 hours of admission. PALS was related to a composite outcome of death and heart failure hospitalization.
Reduced PALS was associated with hypertension, diabetes and Killip class>1 (All p-values<0.05). All measures of LV systolic and diastolic function progressively worsened with reduced PALS and the correlation between GLS and PALS was highly significant (p<0.001, r=-0.71). During follow-up (median 23.0 months IQR, 16.8-26.0) a total of 76 patients (9.0%) reached the composite endpoint. PALS was significantly associated with outcome (HR, 0.88; 95%CI 0.85-0.90, p<0.001), however no independent effect of PALS (1.00; 95%CI 0.99-1.01, p=0.46) was found when adjusting for GLS (HR, 1.20; 95%CI 1.09-1.33, p<0.001), LAmax (HR, 1.02; 95%CI 1.01-1.04, p=0.006) and age (HR, 1.06; 95%CI 1.03-1.08, p<0.001).
PALS provides a composite measure of LV longitudinal systolic function and LAmax and contains no added information when these measures are known.
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Multimodality Imaging in Cardiomyopathy
Abstract Category: 18. Imaging: Echo
Presentation Number: 1316-369
- 2013 American College of Cardiology Foundation