Author + information
Several randomized control trials have reported conflicting results concerning mortality between CABG and PCI. The purpose of this study was to conduct a meta-analysis of recent retrospective studies examining the long-term mortality of patients with multi-vessel coronary artery disease undergoing CABG and PCI.
We searched Medline for retrospective studies comparing long-term (>1 year) outcomes between CABG and PCI for the treatment of multi-vessel coronary artery disease over the past 10 years. Endpoints included: mortality, myocardial infarction (MI), cerebrovascular event (CVE), repeat revascularization, and major adverse cardiac and cerebrovascular events (MACCE).
Eight studies met inclusion criteria. A total of 306,868 patients (155,502 CABG; 151,366 PCI) were identified. Follow-up ranged from 1-8 years. Pooled hazard ratios demonstrated a protective benefit of CABG compared with PCI: mortality HR=0.77 (95%CI 0.75-0.79); MI 0.48 (0.42-0.54); repeat revascularization 0.24 (0.21-0.27); and MACCE 0.51 (0.47-0.55). CABG was not found to be significantly protective for CVE, 0.92 (0.63-1.30).
These findings are consistent with a long-term survival benefit of CABG compared with PCI in patients with multi-vessel coronary artery disease.
Moderated Poster Contributions
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Stable Ischemic Heart Disease: CABG in 2013
Abstract Category: 10. Chronic CAD/Stable Ischemic Heart Disease: Clinical
Presentation Number: 1283M-70
- 2013 American College of Cardiology Foundation