Author + information
- Nicole Martin Bhave,
- Lynn Weinert,
- Megan Yamat,
- Benjamin Freed,
- Victor Mor-Avi,
- Mardi Gomberg-Maitland,
- Amit Patel and
- Roberto Lang
Right ventricular (RV) volume and function assessments are essential in management of pulmonary arterial hypertension. Three-dimensional (3D) echocardiography is limited by acoustic dropout of the RV free wall in dilated ventricles. We hypothesized that a novel method for 3D reconstruction of RV endocardium from 2D echocardiographic images could provide accurate measurements of RV volumes.
27 patients with pulmonary arterial hypertension (26 female) were prospectively recruited for same-day echocardiography and cardiac magnetic resonance (CMR), which was used as a reference. 2D echocardiographic images were acquired with a 3D spatial localization device to allow 3D reconstruction. Anatomic landmark selection on 2D images and 3D reconstruction were performed with dedicated software (Ventripoint) to obtain end-diastolic and end-systolic volumes (EDV, ESV). The method of disks was used to determine RV volumes on CMR. Inter- and intra-observer variability was assessed in 15 patients using coefficients of variation.
Echocardiographic RV volumes correlated well with CMR (EDV, r=0.87; ESV, r=0.88). Inter-observer variability was: EDV, 9±8%; ESV, 10±9%, and RVEF, 11±8%. Intra-observer variability was: EDV, 9±6%; ESV, 11±8%; and RVEF, 11±9%.
This new 3D reconstruction technique provides accurate and reproducible measurements of RV volumes in pulmonary arterial hypertension patients, in whom volumetric measurements are difficult.
Poster Sessions, Expo North
Saturday, March 09, 2013, 10:00 a.m.-10:45 a.m.
Session Title: Pulmonary Hypertension Imaging
Abstract Category: 27. Pulmonary Hypertension
Presentation Number: 1123-154
- 2013 American College of Cardiology Foundation