Author + information
- María Luaces,
- Mariana Paiva,
- Sandra Secades Gonzalez,
- Catarina Vieira,
- Jorge Cabezudo Pedrazo,
- Alejandro García-Muñoz Najar,
- Manuel Medina Garcia,
- Alfonso Antequera-Pérez,
- Leopoldo Pérez de Isla and
- Victoria Cachofeiro
Epicardial adipose tissue (EAT) is metabolically active and releases a variety of adipokines with a potential role in obesity- related heart damage. Little information exists regarding changes in EAT following bariatric surgery.
Morbidly obese patients accepted for bariatric surgery were consecutively recruited. In each case, CMR was performed on a 1.5 T scanner before surgery and 1 year after the procedure. SSPF cine and double IR images were acquired in the 3 orthogonal axes. Manual tracings of the EAT were performed covering both ventricles, as well as endocardial and epicardial ventricular contours. Blood glucose and triglyceride levels were obtained before and after the procedure.
16 patients (81.25% female) reached 1 year follow-up. EAT decreased by 27%, and LV mass decreased by 14% (the table). Glucose and triglyceride levels showed significant amelioration.
Patients undergoing bariatric surgery show a significant decrease in the amount of epicardial adipose tissue and LV mass 1 year after the procedure. This reduction is accompanied by a substantial improvement in metabolic control.
Fondo de Investigaciones Sanitarias (PI09/0871 and PI09/2428).
Table legend. Data are expressed as mean ±mean standard error. BMI= Body mass index. EAT= Epicardial adipose tissue. LVmass: left ventricular mass. LVED: LV end diastolic volume. LVES: LV end systolic volume. LVSV: LV stroke volume. LVEF: LV ejection fraction.
CMR quantification of epicardial fat and LV parameters before and after bariatric surgery.
|Glucose (g/dL)||103.8 ± 6.26||83.9 ± 3.36||P=0.007|
|Triglycerides(mg/dL)||136.50 ± 16.13||93.8±9.85||P=0.022|
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Pericardial Diseases
Abstract Category: 23. Pericardial/Myocardial Disease
Presentation Number: 1250-152
- 2013 American College of Cardiology Foundation