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Bleeding remains a leading complication in patients undergoing cardiac catheterization. It has been suggested that race may be an independent factor affecting risk of bleeding after PCI. It is not clearly known whether there are any racial differences among the bleeding complications 72 hours after cardiac catheterization.
The records of 3817 patients undergoing cardiac catheterization were reviewed and bleeding complications were compared between African Americans and Caucasians. Hierarchical multiple logistic regression analyses were performed using bleeding events within 72 hours as the dependent variable. Results are reported as odds ratios with 95% confidence interval.
There were statistically significant differences in bleeding outcomes between African Americans and Caucasians. These differences remained after adjusting for BMI, hypertension, diabetes, access site, PCI, presence of cardiogenic shock or use of IABP.
In this retrospective analysis of 3817 consecutively enrolled patients undergoing cardiac catheterization, Caucasians were twice as likely to have bleeding complications within 72 hours, as compared to African Americans. Additionally, those with previous chronic lung disease were also twice as likely to have a bleeding event. Post event bleeding was associated with a 2 fold increased chance of developing CHF as well.
|Co-Variants||Odds Ratio||95% CI||P-Value|
|Race (African American)||0.493||0.245–0.991||0.047*|
|Family History of CAD||0.749||0.387–1.448||0.388|
|Prior Heart Failure||1.030||0.495–2.142||0.939|
|Currently on Dialysis||0.323||0.042–2.502||0.280|
|Chronic Lung Disease||1.971||1.044–3.723||0.036*|
|Prior Valve Surgery||0.533||0.064–4.415||0.559|
|Heart Failure within 2 weeks||0.647||0.315–1.332||0.228|
|Arterial Access Site (Femoral)||4.152||1.622–10.627||0.003*|
|New requirement for dialysis||1.324||0.137–12.792||0.805|
Poster Sessions, Expo North
Sunday, March 10, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Contemporary Issues in Cath Lab Performance
Abstract Category: 22. Performance Improvement
Presentation Number: 1218-273
- 2013 American College of Cardiology Foundation