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Prediabetes and prehypertension have been reported to be associated with future risk of diabetes, hypertension and cardiovascular events. There is limited data regarding national trends of prediabetes and prehypertension in otherwise healthy women.
This study utilized 10 year data from National Health And Nutrition Examination Survey (NHANES) from year 2001 to 2010. Women with available fasting blood glucose (FBS) or HbA1C levels were included for prediabetes trends, and those with blood pressure readings were included for prehypertension trends. Women with positive history or lack of data on diabetes, hypertension, use of antihypertensive meds, congestive heart failure, angina, myocardial infarction, stroke and coronary artery disease were excluded from analyses. Baseline characteristics were assessed. Using American Diabetes Association criteria, prediabetes was defined as FBS 100-125 mg/dl or HbA1C 5.7-6.4%. Using JNC 7 criteria, prehypertension was defined as systolic blood pressure 120-139 mm Hgand/or diastolic blood pressure 80-89 mm Hg. Cross-tabulation analysis was then done using Chi square tests to assess significance of change in trends across years. Multivariate analysis was used to examine predictors of prediabetes and prehypertension in the study sample.
FBS and/or HbA1C data was available for 7782 healthy women. The prevalence rates of prediabetes in healthy women were 15.5% for 2001-02, 15.7% for 2003-04, 24.5% for 2005-06, 31.0% for 2007-08 and 28.8% for 2009-10. Systolic and/or diastolic blood pressure data was available for 513 healthy women. The prevalence rates of prehypertension in healthy women were 46.3% for 2001-02, 41.9% for 2003-04, 33.3% for 2005-06, 54.2% for 2007-08 and 50.5% for 2009-10. Chi-square analysis revealed p value of 0.002 and 0.21 for prediabetes and prehypertension trends across all years respectively.
In this cross-sectional analysis of nationally representative sample of healthy women, the prevalence of prediabetes increased significantly over the past 10 years. The prevalence of prehypertension among healthy women remained high and did not change significantly.
Moderated Poster Contributions
Poster Sessions, Expo North
Sunday, March 10, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Hypertension: Patterns, Profiles and Pills
Abstract Category: 25. Prevention: Hypertension
Presentation Number: 1186M-8
- 2013 American College of Cardiology Foundation