Author + information
- Anne Grete Semb,
- Silvia Rollefstad,
- Jonny Hisdal,
- Anne S. Eirheim,
- Desiree van der Heijde,
- Einar Stranden,
- Tore K. Kvien and
- Inge C Olsen
Patients with asymptomatic carotid plaque (a-CP) should receive intensive lipid lowering (LL) treatment in cardiovascular (CV) prevention. We evaluated if CV risk calculators predict the presence of a-CP in patients with inflammatory joint disease (IJD) and if optimizing cut off points in risk calculators will improve this prediction.
CV risk stratification in IJD patients (n= 346) using SCORE, Framingham and Reynolds, in addition to ultrasound of carotid arteries. Cross-tabulations, Chi2 and ROC curves were used to calculate sensitivity/specificity, odds- and likelihood ratio (LR) for identifying a-CP. The ROC closest point (0.1) and 80 % sensitivity were used for optimizing identification of a-CP.
Of patients with SCORE<5% (245), which indicates no need for LL, 94 (38.4%) had a-CP and should receive intensive LL. In patients with SCORE >5% (n=90), indicating a need for moderate LL, 59 (65.6%) had a-CP and should therefore have been categorized to intensive LL. The CV risk calculators are poor predictors of a-CP. (Table). Optimizing the cut off by closest point (0, 1) or 80% specificity did not improve identification of a-CP.
Carotid ultrasound contributes to correct classification of patients with IJD into intensive LL.
Moderated Poster Contributions
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Prevention: Risk Assessment in Primary Prevention
Abstract Category: 24. Prevention: Clinical
Presentation Number: 1232M-9
- 2013 American College of Cardiology Foundation