Author + information
- Shunsuke Kataoka,
- Kozo Okada,
- Masaomi Gohbara,
- Noriaki Iwahashi,
- Kengo Tsukahara,
- Yoshio Tahara,
- Kiyoshi Hibi,
- Masami Kosuge,
- Toshiaki Ebina,
- Satoshi Umemura and
- Kazuo Kimura
Although mean nighttime (sleep) blood pressure (BP) and daytime BP variability are important risk factors for target organ damage, the effect of nighttime BP variability was not fully elucidated in patients with non ST-segment elevation acute coronary syndromes (NSTE-ACS).
In 25 NSTE-ACS patients undergoing coronary intervention (66±6 years, 19 male), we assessd the relationships of nighttime BP variability to left ventricular (LV) hypertrophy, as determined by LV mass index, and carotid intima media thickness (IMT), in comparison with other BP patterns (mean nighttime BP and daytime BP variability). Each BP pattern was analyzed by ambulatory 24-hour blood pressure monitoring (ABPM) data, and BP variability was defined as standard deviation of mean systolic BP.
Higher nighttime BP variability was associated with both increased LV mass index (r=0.49, p<0.05) and IMT (r=0.32, p<0.05) in the simple linear regression analysis (Figure). On the other hand, neither mean nighttime BP nor daytime BP variability was associated with these parameters.
Greater nighttime BP variability was associated with increased LV hypertrophy and IMT, as compared with mean nighttime BP and daytime BP variability. Nighttime BP variability should be considered for the BP treatment of patients with NSTE-ACS.
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Preclinical Manifestations of Hypertension and Arterial Stiffness
Abstract Category: 25. Prevention: Hypertension
Presentation Number: 1276-26
- 2013 American College of Cardiology Foundation