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Studies suggest similar if not worse outcomes in diastolic heart failure when compared to systolic heart failure (HF). Given advancements in treatment, examination of long term outcomes among forms of heart failure merits further study.
Total annual discharges and deaths for patients with a primary diagnosis Systolic, Diastolic, Combined or Unspecified types of HF obtained via the U.S. Department of Health and Human Services Nationwide Inpatient Sample between 2002-2010 were trended. A monte carlo permutation with Bonferroni correction was performed, with annual percentage change (APC) tested for significance via Joinpoint Regression software (v3.5) assuming homoscedasticity.
A total 338,745 deaths occurred from 9,785,936 heart failure admissions. While APC declines (Combined HF −3.2%, Diastolic HF −3.7%, Unspecified HF −4.3%, Systolic HF −9.6%) for all groups remained statistically significant, between 2007-2010, systolic (APC +6.6%) and unspecified (APC +3.1%) HF maintained an insignificant change. Mortality from diastolic HF remained lowest during this time period.
Data suggest current therapies may aid in treatment of diastolic HF greater than previously realized, but recent stagnation following early declines in systolic HF mortality is intriguing. Explanations include a dearth of novel medical interventions, or an aging population in which diastolic dysfunction does not require unique treatment. Further comparisons are needed.
Poster Sessions, Expo North
Saturday, March 09, 2013, 10:00 a.m.-10:45 a.m.
Session Title: Improving Heart Failure Outcomes
Abstract Category: 28. Quality of Care and Outcomes Assessment
Presentation Number: 1114-91
- 2013 American College of Cardiology Foundation