Author + information
- Mehmet Ergelen,
- Huseyin Uyarel,
- Seref Kul,
- Servet Altay,
- Erkan Ayhan,
- Turgay Isik,
- Tuba Kemaloglu,
- Mehmet Gul,
- Gokhan Cicek,
- Abdurrahman Tasal and
- Mehmet Eren
We sought to examine in-hospital and long-term outcomes of red blood cell (RBC) transfusions in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).
2537 consecutive STEMI patients (mean age 56.2 ± 11.7 years, 2111 male, 426 female) undergoing primary angioplasty were retrospectively enrolled into the present study. Patients were categorized according to whether they received RBC transfusions during hospitalization. Clinical characteristics, in-hospital and long-term outcomes of primary PCI were analysed.
Of consecutive 2537 patients, 88 (3.4%) received RBC transfusions during the index hospitalization. The transfused patients were older than non-transfused patients (mean age 63.6 ±12.1 vs 56.2±11.8, p<0.001). Compared to non-transfused patients; female gender and hypertension were more prevalent in transfused patients (45.4% vs 15.8%, p<0.001; 52.3% vs 40.7%, p=0.04, respectively). Baseline values of hematocrit and hemoglobin were lower in patients receiving transfusion (33±6.2 % vs 40.2±4.7 %, p<0.001; 11.1±2.3 mg/dl vs 13.7±1.6 mg/dl, p<0.001 respectively). The transfused patients had significantly higher in-hospital and long-term mortality (for in-hospital mortaliy: 10.2% vs 2.7 %, p<0.001; for long -term mortality: 14.1% vs 5.1%, p=0.001). By multivariate Cox regression analysis in all 2537 patients; RBC transfusion was found a powerful independent predictor of in-hospital cardiovascular mortality (odds ratio [OR] 8.31, p<0.001).
These results suggest that RBC transfusion is associated with increased in-hospital and long-term mortality in patients with STEMI undergoing primary angioplasty.
Poster Sessions, Expo North
Sunday, March 10, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Percutaneous Coronary Intervention for AMI: Predictors of Outcome
Abstract Category: 1. Acute Coronary Syndromes: Clinical
Presentation Number: 1216-214
- 2013 American College of Cardiology Foundation